The iPhone 5 reviews reviewed: It's a hit (but...)

Featured

8 hrs.

Wilson Rothman

Every time an Apple product comes out, a select few reviewers get first dibs on testing it first. On Tuesday night, the iPhone 5 reviews went live, and by and large, they were positive. There was one consistent gripe throughout ? a change in how the iPhone connects to chargers and accessories ? but reviews overall carried the "best iPhone ever" theme.

David Pogue, at the New York Times, identifies the three factors that have made the iPhone a success ? design, components and compatibility ? and says that while the iPhone 5 excels at the first two, its new connector, which makes older docks and chargers obsolete, takes away points in the compatibility department. (Pogue does point out, however, that the new connector is smaller, sturdier and easier to use than the old one, because it doesn't matter which side is up when you plug it in.)

At USA Today, Ed Baig?says that after more than two years with the same 4/4S look, there's pent-up demand for a new Apple design: "What I detect this time is lust," he writes. At the same time, after evaluating the product, he says that Apple has met expectations "with a gem."

The connector issue does come up. "You can't blame folks for making a fuss," writes Baig, but "most of these people will probably buy the darn phone anyway, and do so, I suspect, with glee."

The Wall Street Journal's Walt Mossberg perhaps overstates things with the headline "The iPhone takes to the big screen." After all, a 4-inch 16x9 screen is not big compared to most competitors. Also, Mossberg harps on the new Maps app (which may be problematic, but is a feature of iOS 6 ??available as a free download Wednesday to most iPhone owners ? not the new iPhone).?

Still, his review is generally positive, praising the speed of the new chip and the 4G LTE cellular data connection. Mossberg does have a beef with, you guessed it, that new connector, a "design change that's already rankling people."

CNet's Scott Stein named it an Editors' Choice, and said it "adds everything we want in an iPhone" (4G, bigger screen, new processor) and that it's "absolutely the best iPhone to date."

So what's bad? Stein laments the fact that Sprint and Verizon models can't handle a voice call and data interaction simultaneously. He also blasted that durned connector, and the fact that even the new, larger screen is way smaller than the ones found on competing Android devices. No surprises, but all things to take into consideration.

TechCrunch's MG Siegler calls the phone "an absolute home run" and goes on and on about how light it is, specifically that its lightness "just doesn't seem real." (We also said something to this effect after the launch.)

As for the apps that don't yet fit the 4-inch screen, Siegler says "it's really not a big deal."?

Siegler points out something that hasn't really made the rounds: The headphone jack is on the bottom of the iPhone 5, like it is on an iPod Touch.

Notably absent from the review circus (at time of publication) is tech site The Verge, which is typically among the chosen reviewers.

So while reviewers agree it's the best iPhone yet, the question remains, how does it fare compared to a Samsung Galaxy S III or other competing smartphones? Despite some criticism of the?Android OS and some of Samsung's add-on software features,?nobody seems to want to say the iPhone 5 slays the competition outright. Most reviewers answered instead with an "it's up to you" shrug. That is, if you want a really big screen, then go for one of the Android phones, but, as Mossberg puts it, the iPhone 5 is "an excellent choice."

Wilson Rothman is the Technology & Science?editor at NBC News Digital. Catch up with him on Twitter at @wjrothman, and join our conversation on Facebook.

Source: http://www.nbcnews.com/technology/gadgetbox/iphone-5-reviews-reviewed-its-hit-1B5978659

casey anthony video recess appointment eastman kodak eastman kodak richard cordray shannon de lima joe torre

Discovery of reprogramming signature may help further stem cell-based regenerative medicine research

Discovery of reprogramming signature may help further stem cell-based regenerative medicine research

Wednesday, September 19, 2012

Salk scientists have identified a unique molecular signature in induced pluripotent stem cells (iPSCs), "reprogrammed" cells that show great promise in regenerative medicine thanks to their ability to generate a range of body tissues.

In this week's Proceedings of the National Academy of Sciences, the Salk scientists and their collaborators at University of California, San Diego, report that there is a consistent, signature difference between embryonic and induced pluripotent stem cells. The findings could help overcome hurdles to using the induced stem cells in regenerative medicine.

"We believe that iPSCs hold a great potential for the treatment of human patients," says Juan Carlos Izpisua Belmonte, a professor in Salk's Gene Expression Laboratory and the senior author on the paper. "Yet we must thoroughly understand the molecular mechanisms governing their safety profile in order to be confident of their function in the human body. With the discovery of these small, yet apparent, epigenetic differences, we believe that we are now one step closer to that goal."

Embryonic stem cells (ESCs) are known for their "pluripotency," the ability to differentiate into nearly any cell in the body. Because of this ability, it has long been thought that ESCs would be ideal to customize for therapeutic uses. However, when ESCs mature into specific cell types, and are then transplanted into a patient, they may elicit immune responses, potentially causing the patient to reject the cells.

In 2006, scientists discovered how to revert mature cells, which had already differentiated into particular cell types, such as skin cells or hair cells, back into a pluripotent state. These "induced pluripotent stem cells" (iPSCs), which could be developed from the patient's own cells, would theoretically carry no risk of immune rejection.

However, scientists found that iPSCs had molecular differences from embryonic stem cells. Specifically, there were epigenetic changes, chemical modifications in DNA that might alter genetic activity. At certain points in the iPSC's genome, scientists could see the presence of different patterns of methyl groups when compared to the genomes of ESCs. It seemed these changes occurred randomly.

Izpisua Belmonte and his colleagues wanted to understand more about these differences. Were they truly random, or was there a discernable pattern?

Unlike previous studies, which had primarily analyzed iPSCs derived from only one mature type of cells (mainly connective tissue cells called fibroblasts), the Salk and UCSD researchers examined iPSCs derived from six different mature cell types to see if there were any commonalities. They discovered that while there were hundreds of unpredictable changes, there were some that remained consistent across the cell types: the same nine genes were associated with these common changes in all iPSCs.

"We knew there were differences between iPSCs and ESCs," says Sergio Ruiz, first author of the paper, "We now have an identifying mark for what they are."

The therapeutic significance of these nine genes awaits further research. The importance of the current study is that it gives stem cells researchers a new and more precise understanding of iPSCs.

###

Salk Institute: http://www.salk.edu

Thanks to Salk Institute for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 27 time(s).

Source: http://www.labspaces.net/123629/Discovery_of_reprogramming_signature_may_help_further_stem_cell_based_regenerative_medicine_research

work hard play hard tim ferriss wmt human nature arkansas football howard johnson blackhawks

Facebook reorganises engineering teams to build faster on mobile

CBR Staff Writer Published 14 September 2012

The social network users have been shifting from accessing it on desktop computers or laptops to smartphones and tablet computers

Social network Facebook has re-organised its engineering teams to make it more mobile friendly to target the mobile users.

Facebook director of product management Peter Deng said that the company has re-organized to build faster on mobile.

"In the past six months we transplanted mobile engineers to the other teams," Deng said.

"Slowly, over time we are making everyone a mobile engineer."

Facebook believes that social network users are shifting from desktop computers or laptops to smartphones and tablet computers, where the company is not faring well in monetising ads.

Facebook product manager Mick Johnson told AFP that about 7,000 different models of mobile devices are used daily to connect with Facebook and the challenge is to tailor experiences for each gadget.

According to Facebook, a focus on HTML 5 technology to link throughout the spectrum of smartphones using mobile Web browsers resulted in lackluster results.

"The performance wasn't what our users expected and we weren't happy with it either," Johnson said.

The smartphone market is dominated by Android and Apple devices.

Facebook has begun Android and iOS training sessions which are anticipated to have 200 to 300 engineers trained by the end of 2012.

In August 2012, Facebook had released the new version 5.0 of its applications for Apple's iPhone and iPad which will allow faster access for users who access the service through mobile devices.

Source: http://desktops.cbronline.com/news/facebook-reorganises-engineering-teams-to-build-faster-on-mobile-140912

giada de laurentiis howard hughes nationwide race wanderlust gone tyler perry good deeds pretty in pink

Scientists use prosthetic device to restore and improve impaired decision-making ability in animals

Scientists use prosthetic device to restore and improve impaired decision-making ability in animals

Friday, September 14, 2012

Imagine a prosthetic device capable of restoring decision-making in people who have reduced capacity due to brain disease or injury. While this may sound like science fiction, researchers at Wake Forest Baptist Medical Center have proven for the first time that it is possible in non-human primates, and believe that one day it will be possible in people.

In essence, the scientists used an electronic prosthetic system to tap into existing circuitry in the brain at the cellular level and record the firing patterns of multiple neurons in the prefrontal cortex, the part of the brain involved in decision-making. They then "played" that recording back to the same brain area to electrically stimulate decision-based neural activity. Not only did it restore function, in some cases, it also improved it.

"The prosthetic device is like 'flipping a switch' to turn on a decision in real time," said Sam Deadwyler, Ph.D., professor of physiology and pharmacology at Wake Forest Baptist, and senior author of the study, which is published in the Sept.14 issue of the Journal of Neural Engineering.

In the study, the scientists trained five monkeys to match multiple images on a computer screen until they were correct 70 to 75 percent of the time. First, an image appeared on the screen, which the animals were trained to select using a hand-controlled cursor. The screen then went blank for up to two minutes, followed by the reappearance of two to eight images, including the initial one, on the same screen.

When the monkeys correctly chose the image they were shown first, the electronic prosthetic device recorded the pattern of neural pulses associated with their decision by employing a multi-input multi-output nonlinear (MIMO) mathematical model, developed by researchers at the University of Southern California.

In the next phase of the study, a drug known to disrupt cognitive activity, cocaine, was administered to the animals to simulate brain injury. When the animals repeated the image-selection task, their decision-making ability decreased 13 percent from normal. However, during these "drug sessions," the MIMO prosthesis detected when the animals were likely to choose the wrong image and played back the previously recorded "correct" neural patterns for the task.

According to the study findings, the MIMO device was exceedingly effective in restoring the cocaine-impaired decision-making ability to an improved level of 10 percent above normal, even when the drug was still present and active.

"The basis for why the MIMO prosthesis was effective in improving performance was because we specifically programmed the model to recognize neural patterns that occurred when the animals correctly performed the behavioral task in real time, which is a unique feature of this particular device," said Robert E. Hampson, Ph.D., associate professor of physiology and pharmacology at Wake Forest Baptist, and lead author of the study.

"Based on the findings of this study, we hope in the future to develop an implantable neuroprosthesis that could help people recover from cognitive deficiencies due to brain injuries," Hampson said.

###

Wake Forest Baptist Medical Center: http://www.wfubmc.edu

Thanks to Wake Forest Baptist Medical Center for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 68 time(s).

Source: http://www.labspaces.net/123513/Scientists_use_prosthetic_device_to_restore_and_improve_impaired_decision_making_ability_in_animals

whitney cummings msnbc i will always love you maine caucus whitney houston has died blue ivy carter whitney houston death

Decals or Automotive Wraps - Fiberglass RV

?

Yesterday, 02:22 PM	? #1
Member ? Name: Bonnie and Claude Trailer: 1975 Boler 1300 Ontario Posts: 90	Decals or Automotive Wraps We are toying with adding some sort of graphic to our Boler and were wondering if anyone had added decals or automative wraps to their fibreglass trailers. If so, any suggestions on what works best--decals or wraps? Can you still use the Poli-glo products to clean and wax the trailer without damaging the graphics? (May be best just to hang something in the window.) And...saw some units that have a grapic on the underside of the front window cover. How are the graphics attached to the cover? ' + '?' + google_ads[i].line2 + '?' + google_ads[i].line3 + '?' + '' + google_ads[i].visible_url + ' '; } } '' } if (google_ads[0].bidtype == "CPC") { /* insert this snippet for each ad call */ google_adnum = google_adnum + google_ads.length; } document.write(s); return; } google_ad_client = 'ca-pub-7757781251671730'; google_ad_channel = '6058081585'; google_ad_output = 'js'; google_max_num_ads = '6'; google_ad_type = 'text'; google_feedback = 'on'; // --> __________________
?

Yesterday, 09:22 PM	? #2
Member ? Name: Dave & Paula Brown Trailer: 1990 13ft. Scamp Custom (L-Shaped kitchen counter top). Arizona Posts: 57	decals or wraps I don't know about wraps, but I to thought about using them. I did notice that when I applied Red Maxx Pro to my trailer all but the decals looked great. The decals (SCAMP) appeared to have a "milky" look to them, as well as the plastic weep hole covers on the windows. The Red Maxx eventually peeled off the plastic, but is still on the decals. Hope this helps. ' + '?' + google_ads[i].line2 + '?' + google_ads[i].line3 + '?' + '' + google_ads[i].visible_url + ' '; } } '' } if (google_ads[0].bidtype == "CPC") { /* insert this snippet for each ad call */ google_adnum = google_adnum + google_ads.length; } document.write(s); return; } google_ad_client = 'ca-pub-7757781251671730'; google_ad_channel = '0614124275'; google_ad_output = 'js'; google_max_num_ads = '6'; google_ad_type = 'text'; google_feedback = 'on'; // --> __________________
?

Today, 12:29 AM	? #3
Senior Member ? Name: Jimbo Trailer: 1971 Trails West Campster/1980 Scamp 13 California Posts: 154	Quote: Originally Posted by David B. I don't know about wraps, but I to thought about using them. I did notice that when I applied Red Maxx Pro to my trailer all but the decals looked great. The decals (SCAMP) appeared to have a "milky" look to them, as well as the plastic weep hole covers on the windows. The Red Maxx eventually peeled off the plastic, but is still on the decals. Hope this helps. Thanks for the tip about the decals. I wasn't to use red maxx and was going to out in new decals and just go over them with RMP. Maybe I'll mask them off first __________________
?

Today, 12:36 AM	? #4
Member ? Name: Jeff Trailer: 1977 13-foot Scamp Washington Posts: 60	One of the wildest Bolers I've seen is called the Bodo Boler. It was built by Linda Bodo, an author, columnist and eco-deco designer from Edmonton, Alberta, Canada. Here's is a web page telling the story of the Boler she modified: The Bold and the BodoBoler ? Absolute Bodo Here's a video where she describes interior and exterior mods. At 3:08 minutes into the video she shows how she applied the vinyl wrap on the outside: The Bold and The Boler: Interior and Exterior Update...The Home Stretch! on Vimeo I believe she sold this trailer last year. I don't know where it is now. Good luck! Jeff __________________
?

Today, 06:37 AM	? #5
Senior Member ? Name: Bob Trailer: 1973 Hunter Compact-II & 1994 13' Lil' Bigfoot California Posts: 443	If you look in the accessories - rv's section of eBay and search for stripes, graphics or decals, you will get hundreds of hits. Mostly for surplus graphics and stripes, but also a few custom sources. Using regular RV graphics will help assure that they stick around... __________________
?

Today, 07:33 AM	? #6
Member ? Name: Bonnie and Claude Trailer: 1975 Boler 1300 Ontario Posts: 90	Quote: One of the wildest Bolers I've seen is called the Bodo Boler. It was built by Linda Bodo, an author, columnist and eco-deco designer from Edmonton, Alberta... Thanks for the links. I was following her renovations for a while but forgot about it. She has a website: Absolute Bodo that doesn't appear to have been updated since December 2011 and a Facebook page. Sent her a FB message asking what happened to her Boler. Wonder how the peel-and-stick fared over time. Ours has a nice shiny marine paint which is why I thought I'd ask others about adding graphics and how they would look over the long-term. I'd love a bit of colour (yup...that's a Canadian 'u' in my spelling), but don't want to 'hurt' our little unit. __________________
?

Today, 07:35 AM	? #7
Member ? Name: Bonnie and Claude Trailer: 1975 Boler 1300 Ontario Posts: 90	Quote: If you look in the accessories - rv's section of eBay and search for stripes, graphics or decals, you will get hundreds of hits.... Great idea, Bob. Will check it out after the weekend. Off to start closing our stationary Golden Falcon this weekend in preparation for Boler Season. __________________
?

Today, 07:39 AM	? #8
Member ? Name: Bonnie and Claude Trailer: 1975 Boler 1300 Ontario Posts: 90	Quote: ... I did notice that when I applied Red Maxx Pro to my trailer... decals (SCAMP) appeared to have a "milky" look to them... That is exactly the type of information I was looking for. Thank you. Think I'll continue to collect information before deciding whether or not to add anything to the Boler's exterior. __________________
?

Today, 07:41 AM	? #9
Member ? Name: Bonnie and Claude Trailer: 1975 Boler 1300 Ontario Posts: 90	Quote: Thanks for the tip about the decals. I wasn't to use red maxx and was going to out in new decals and just go over them with RMP. Maybe I'll mask them off first Colour me blonde (ok greying blonde) but what is RMP? Once you've done, can you post the results? Thanks. __________________
?

Today, 08:55 AM	? #10
Senior Member ? Name: Jimbo Trailer: 1971 Trails West Campster/1980 Scamp 13 California Posts: 154	My bad. Late at nite. Red Maxx Pro. Basically a professional floor coating many here have used to give a super deep sheen back to their trailers. Check a thread here called this us not poliglow Check this out NOT Poliglow...Time will tell.. __________________
?

Today, 09:05 AM	? #11
Junior Member ? Trailer: 1989 Scamp 13 ft Posts: 3	Yes, you can still use the polish. I bought decals from carstickers.com You can get about anything youre interested in! __________________
?

Today, 09:12 AM	? #12
Senior Member ? Name: Jimbo Trailer: 1971 Trails West Campster/1980 Scamp 13 California Posts: 154	Quote: Originally Posted by Marty Brian Yes, you can still use the polish. I bought decals from carstickers.com You can get about anything youre interested in! Nice tip. Thx ' + '?' + google_ads[i].line2 + '?' + google_ads[i].line3 + '?' + '' + google_ads[i].visible_url + ' '; } } '' } if (google_ads[0].bidtype == "CPC") { /* insert this snippet for each ad call */ google_adnum = google_adnum + google_ads.length; } document.write(s); return; } google_ad_client = 'ca-pub-7757781251671730'; google_ad_channel = '3472616267'; google_ad_output = 'js'; google_max_num_ads = '6'; google_ad_type = 'text'; google_feedback = 'on'; // --> __________________
?

Currently Active Users Viewing This Thread: 3 (2 members and 1 guests)

Mireille L, Terry G

? Upcoming Events

Source: http://www.fiberglassrv.com/forums/f56/decals-or-automotive-wraps-54407.html

ray allen Savages Home Run Derby 2012 San Diego fireworks steve nash july 4th higgs boson

Microsoft now owns web domains for ?Halo? series through ?Halo 9?

In a bout of rather absurd brand protection (or perhaps a reveal as to just how long they?ll be milking this series!), Microsoft has purchased the website domains names of Halo4 (understandably), Halo5, Halo6, Halo7, Halo8, and Halo9. Why so soon? They probably learned their lesson after missing the chance to buy the ?halo.com? domain [...]

Source: http://thegamestribe.com/news/microsoft-now-owns-web-domains-for-%E2%80%98halo%E2%80%99-series-through-%E2%80%98halo-9%E2%80%B2/

kansas state last house on the left last house on the left rich forever mixtape blow the unit bob weston

US launches national defense satellite

VANDENBERG AIR FORCE BASE, Calif.?? An Atlas 5 rocket carrying a classified satellite for the U.S. National Reconnaissance Office has lifted off from Vandenberg Air Force Base on the central California coast.

The launch vehicle's main engine ignited Thursday at 2:39 p.m. PDT for a mission described only as being in support of national defense.

It's the fourth launch this year for the NRO, which operates the nation's system of intelligence-gathering satellites. The launch was delayed six weeks because of launch range equipment problems.

The Atlas is also carrying 11 tiny satellites known as Cubesats to conduct research on subjects ranging from space weather to tracking maritime shipping containers.

The Cubesats include projects of four universities.

Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.msnbc.msn.com/id/49025329/ns/technology_and_science-space/

tampa bay buccaneers birdman whip it gabby giffords gabby giffords geithner gabrielle giffords